- The neonatal period: 60-90% of infants have transient gynecomastia due to transplacental transfer of maternal estrogens.
- Puberty: 48-64% of boys at puberty have gynecomastia. Usually peak age of onset is between 13 and 14 years, followed by a decline in late teenage years.
- Late in life: The highest prevalence of gynecomastia is seen among men aged 50-80 years.
- Grade IA--primarily fatty breast tissue. Suction-assisted lipectomy can be used with great success.
- Grade IB--primarily fibrous breast tissue
- Grade IIA--primarily fatty breast tissue. Suction-assisted lipectomy can be used with great success.
- Grade IIB--primarily fibrous breast tissue
Grade IV --severe hypertrophy (more than 500 gm of breast
tissue), grade 2 or 3 ptosis
Gynecomastia--eMedicine article, June 9, 2006; Ali Fawzi, MD