The lipomatous tissue is characterized by normal-sized or smaller-than-expect fat cells. The appearance and localization of the lipomata can be variable and have been divided into 3 types by Donhauser and colleagues. More than one type may be present in a patient.Type I: Diffuse lipomatosis of the neck (horse-collar lipomata)
The diagnosis is made by clinical history and physical exam. Other problems (simply obesity, sarcoma, lymphoma, etc) must be kept in mind. Currently there are no laboratory parameters specific to this condition. The lipomata of Madelung's show no tendency toward malignancy, but may cause problems (sleep apnea, tracheal obstruction, neuropathy) simply due to location and size. Patients should be advised to loose weight and abstain from alcohol. These, however, will not reverse or stop the progression of the disease once it is established.
- Adénolipomatose symétrique Launois-Bensaude (French)
- Launois-Bensaude syndrome
- Brodie's Syndrome II
- Buschke’s disease
- Buschke's syndrome II
- Madelung-Launois-Bensaude syndrome
- Lipoma by Robert A Moraru, MD; eMedicine Article
- Madelung's Disease in a Patient with Diabetes Mellitus by HS Dokmetas, MD and others; Skin Med, Dermatology for the Clinician, Sept/Oct 2007, Vol 6, Issue 5, pp247-249
- Launois- Bensaude Syndrome (Madelung' s Disease); Bojanic Petar, Simovic Ivan; Dermatology Online Journal 7(2): 9
- Head and Neck Cancers Associated with Madelung's Disease; Chan ES, Ahuja AT, King AD, Lau WY; Ann Surg Oncol, 1999 Jun; 6 (4):395-7--Abstract
- An Unusual Entity for a Plastic Surgeon: Madelung Syndrome; Plastic & Reconstructive Surgery. 117(2):693-695, February 2006; Civelek, Birol M.D.; Celebioglu, Selim M.D.; Ozpolat, Berkant M.D.