Saturday, November 24, 2007

Diabetic Mastopathy

"Diabetic mastopathy, also known as sclerosing lymphocytic lobulitis, is characterized by benign, firm, painless, mobile, irregular masses most often found in both breasts of patients with a long history of Type I diabetes. Diabetic mastopathy rarely occurs in Type II diabetics. Patients with diabetic mastopathy often have a history of poor glucose control with related complications such as retinopathy, neuropathy, and nephropathy. Rarely, patients with other endocrine diseases will present with diabetic mastopathy.

The incidence of diabetic mastopathy varies widely: from 1 in 1,700 women screened in a breast clinic to 13% of Type I diabetic women ages 20 to 40 in a diabetic clinic."

(A) keloidal-like stromal fibrosis (20x magnification, H&E stain) and (B) mild lymphocytic lobulitis and surrounding fibrosis (10x magnification, H&E stain) complete the classic pathologic description of diabetic mastopathy.

The above text and photos are from a nice article in the current (November 2007) issue of Contemporary Surgery Journal by Matthew Borgo, BA, Shaheen Zakaria, MD, and David Farley, MD. It can be accessed online (with free registration) here. It is worth reading.

You will also find a nice video library of surgical techniques at the Contemporary Surgery website. Check it out.

No comments: