Six cutaneous metastatic carcinomas during this period of study comprised 6.5% of total cutaneous cancer and accounted for 0.6% of total malignancy. The patients included 2 men and 4 women (male-female ratio = 1:2), and their ages ranged from 37 to 55 years (mean, 45.2 years). No patients with these lesions were in the first 3 decades of life, and the 6 patients who had these lesions were between the fourth and sixth decades.
The breast, stomach, lung, uterus, large intestine, and kidneys are the most frequent organs to produce cutaneous metastases. Cancers that have the highest propensity to metastasize to the skin include melanoma (45% of cutaneous metastasis cases), breast (30%), nasal sinuses (20%), larynx (16%), and oral cavity (12%). Because breast cancer is so common, cutaneous metastasis of breast cancer is the most frequently encountered type of cutaneous metastasis in most clinical practices. Although some tumors are very common, they may not necessarily eventuate in metastasis in a manner that parallels their incidence in the overall population. For example, prostate cancer is very common, but cutaneous metastasis from prostate carcinoma is relatively uncommon……..
The mortality rate is high in patients with cutaneous metastases. The appearance of cutaneous metastases signals widespread metastatic disease, resulting in a poor prognosis. Patients often survive for a short period, depending on the type of carcinoma, but this is changing. Exciting advances in chemotherapy have greatly increased survival in recent years.