As people age they may develop more. Sometimes they seem to erupt during pregnancy, following hormone replacement therapy or as a result of other medical problems. They are most likely hereditary and not caused by sun exposure. They often are found on the trunk and on the face where the facial skin meets the scalp. They may be oval spots less than a fraction of an inch across, or may form long Christmas tree like patterns on the torso.
Clothing rubbing against them may irritate and make them grow larger. Alpha-hydroxy lotions and mild steriod creams may help this. If they get very itchy, irritated, or bleed easily they should be removed. When a seborrheic keratosis turns black, it may be difficult to distinguish it from a skin cancer without a biopsy.
Removal is often done using liquid nitrogen (cryosurgery). Another treatment done (as they are superifical–"pasted-on") consist of scraping off the lesion with a curette (ED&C). This is more useful when only a few need to be done or when one spot needs a biopsy (as the scrapings can be sent to the lab). Sometimes they are burnt off with an electric needle or laser.
Liver or age spots are solar lentigines. They are benign lesion that occur on sun-exposed areas of the body. The backs of the hands and face are the most common areas. They tend to increase in number with age. They can vary in size from 0.2 to 2 cm. Lenigines are flat, dark lesions that usually have discrete borders and may have an irregular shape. They are are caused by a marked increase in the number of pigment cells (melanocytes) located in the superficial layers of the skin. Lentigines are benign and no treatment is necessary. For cosmetic purposes, some are treated with cryotherapy, hydroquinone preparations (bleaching creams), retinoids, chemical peels or lasers. Preventive measures include avoidance of excessive sunlight. If a lesion develops a highly irregular border, changes in pigmentation, or changes in the thickness, then a biopsy should be done to rule out cancer.
Actinic keratosis, unlike seborrheic keratoses (AK’s), are from sun damage. They are also called solar keratosis, sun spots, or precancerous spots. They appear as a scaly or crusty bump on the skin surface. They range in size from as small as a pinhead to over an inch in diameter. AK’s may be light or dark, tan, pink, red, a combination of these, or the same color as the skin. They may be flat or raised in appearance. They may disappear only to reappear later. Half of all keratosis will go away on their own if one avoids all sun for a few years (difficult to do). AK’s appear on sun exposed areas: face, ears, bald scalp, neck, backs of hands and forearms, and lips.
Actinic keratosis can be the first step in the development of skin cancer. They are pre-cancer. It is estimated that 10-15 % of active lesions will progress to squamous cell carcinoma (SCC). The presence of AK’s indicates that sun damage has occurred. This increases the likelihood of any kind of skin cancer, not just SCC, can develop. People with AK’s are more likely to develop melanoma also. Sun exposure is the cause of almost all actinic keratoses. So use your sunscreen. Don’t forget the lip balm with sunscreen. Wear your hats, preferably wide brimmed.
Cryosurgery freezes off the lesions through application of liquid nitrogen. This is done with a special spray device or cotton-tipped applicator. It does not require anesthesia and produces no bleeding. The longer the spot is frozen the better the chance it will never come back. Longer freezes can result in hypopigmented areas.
Curettage scrapes the lesion off and may be used as a biopsy specimen. Bleeding is controlled by cautery (application of an acid or heat produced by an electric needle).
Shave Removal utilizes a scalpel to shave the keratosis (provides a specimen). As with curettage, the base of the lesion is destroyed and the bleeding stopped by cauterization.
Chemical Peels make use of acids (Jessners solution and /or trichloroacetic acid) applied over the area. The top layers of the skin are "peeled" off by controlled burning (done by the acid strength used and time left on the skin). It may take up to seven days for the area to heal. Redness and soreness associated with the peel usually disappear after a few days.
Topical creams used to treat keratoses is an effective solution when there are numerous lesions. Aldara works by stimulating the body’s immune system to "recognize" these precancerous lesions and treat them. This ointment is applied to the affected areas twice weekly for 6-12 weeks. 5-fluorouracil (Efudex, Carac) cream works by directly attacking the precancerous cell. This ointment is applied once or twice daily for 2-4 weeks. Treatment leaves the affected area temporarily reddened and raw. The more raw and inflamed the skin becomes, the better the end result. Solaraze gel is a non-steroidal medication that also works fairly well on AK’s. This ointment is applied twice daily for 90 days.